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The blockbuster diabetes drug Ozempic could be manufactured for less than $5 a month, even as Novo Nordisk charges close to $1,000 per month for the injection in the U.S. before insurance, a study released Wednesday suggests. The study also comes after years of political pressure on Novo Nordisk and other drugmakers to slash high costs of diabetes care, especially insulin. Ozempic can generally be produced for less than various forms of insulin, according to the study published in JAMA Network Open. Novo Nordisk's list price for a monthly package of Ozempic is $935.77 before insurance and other rebates. In a statement on Wednesday, Novo Nordisk declined to provide production costs for Ozempic and its weight loss drug counterpart Wegovy.
Organizations: Nordisk, Yale University, King's College Hospital, Novo Nordisk, JAMA, Ozempic, University of Liverpool Locations: U.S, London
In a room crowded with people in suits, the sponsorship deal with brewing giant AB InBev was met with beaming smiles and the clinking of beer bottles by many of those in attendance. AB InBev is the latest company to participate in The Olympic Partner (TOP) program – the highest level of Olympic sponsorship – alongside the likes of Coca-Cola, Visa and Deloitte. AB InBev said that it would not reveal the cost of its deal with the IOC. Stuart C. Wilson/Getty Images for AB InBevThe IOC and AB InBev see the deal as part of a wider market demand for non-alcoholic drinks which, despite being in circulation for decades, have had a recent surge in popularity. Some brands have found ways to navigate France’s restrictive laws when it comes to alcohol advertising.
Persons: Thomas Bach gushed, ” Bach, , ” Andrew Misell, Kin Cheung, Sportcal, Michel Doukeris, Thomas Bach, Stuart C, Wilson, Molson Coors, ” Marcel Marcondes, “ Corona Cero, Marcondes, Bach, Garde, ” Ian Gilmore, “ Corona, ” Alex Barker, ” Barker, Xavier Laine Organizations: CNN, Olympic Committee, InBev, IOC, Corona, Cortina, Alcohol, CNN Sport, Cola, Visa, Deloitte, Health, WHO, Centers for Disease Control, University of Liverpool, , Getty, AB InBev, Heineken, Molson, Games, Alcohol Health Alliance, University of Derby, rugby’s, Nations, Guinness, Stade de France, French rugby, Wales, TOP Locations: London, Corona Cero, Paris, Milan, Los Angeles, Tokyo, Corona, Garde
Read previewThe popular Paleo diet is based on the belief that we are better off eating like our ancestors by sticking to a largely meat-heavy diet. "One way to think about it is as soon as anybody tells you that the Paleo diet was one thing, you can stop listening," said Pontzer, who wasn't involved in the study. The paleo diet is a high-protein diet that emphasizes unprocessed foods. AdvertisementThere is no one Paleo dietThis isn't the only research that disproves the model often held up by proponents of the modern-day definition of the Paleo diet. What's clear is that a meat-heavy diet isn't reflective of what people ate thousands of years ago.
Persons: , Randy Haas, Herman Pontzer, Pontzer, wasn't, Haas, Loren Cordain Organizations: Service, Business, University of Wyoming, Duke University, University of Liverpool, BI Locations: Peru, Patjxa, Germany
Share Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailNew 'Super League' plan is provoking negative reaction, lecturer saysKieran Maguire, football finance lecturer at the University of Liverpool, says a 'European Super League' for soccer is unlikely to take place in its current format, amid vocal fan opposition.
Persons: Kieran Maguire Organizations: League, University of Liverpool Locations: European
The rarity of wood preservation at early archaeological sites - it is perishable over time - means scientists have little understanding of how early humans used it. "Wood can be shaped into a variety of forms making it an excellent construction material that is strong and durable," Barham added. The Kalambo Falls logs were determined to be from about 476,000 years ago. Wooden tools for foraging and hunting are known from about 400,000 years ago. "Use of wood in this way suggests the cognitive ability to these early humans was greater than we have believed based on stone tools alone."
Persons: Larry Barham, Barham, Geoff, heidelbergensis, Will Dunham, Daniel Wallis Organizations: University of Liverpool, REUTERS, Aberystwyth University, Thomson Locations: Zambia, Handout, Africa's, England, Wales, Morocco, Kalambo, Clay, Israel, Washington
CNN —Archaeologists have unearthed the oldest known wooden structure, and it’s almost half a million years old. The wooden structure has no real parallel in the archaeological record, according to the study. The wooden structure was found at an archaeological site upstream of Kalambo Falls in Zambia. Researchers aren’t certain which species of ancient human made the structure and wooden tools, but it is highly unlikely to have been our own. Larry Barham (right), professor of archaeology at the University of Liverpool, carefully uncovers the wooden structure on the riverbank with a fine spray.
Persons: , “ It’s, Geoff, Ya’aqov, It’s, Larry Barham, Annemieke, Milks, wasn’t Organizations: CNN —, University of Aberystwyth, Aberystwyth University, Lincoln, University of Liverpool, University of Reading Locations: Zambia —, United Kingdom, Kalambo, Zambia’s, Tanzania, Kalambo Falls, Zambia, Israel, Europe, what’s
NEW YORK (AP) — Researchers have uncovered a simple structure from the Stone Age that may be the oldest evidence yet of early humans building with wood. But it is much more complex than I thought.”Barham and his team dug up the log structure — plus a handful of wooden tools — from a riverbed site that sits above a waterfall in Zambia. They think the crossed logs could have been the base for a bigger structure like a walkway or a platform. The log structure was made at least 476,000 years ago, while the wood tools are slightly younger, under 400,000 years old. ___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group.
Persons: It's, , Larry Barham, ” Barham, Barham, ’ ” Barham, couldn't, Geoff, , Dirk Leder, Annemieke Milks, , ” Milks Organizations: , University of Liverpool, telltale, Aberystwyth University, Cultural Heritage, University of Reading, Associated Press Health, Science Department, Howard Hughes Medical Institute’s Science, Educational Media Group, AP Locations: Nature, Zambia, Wales, Africa, Germany’s, Saxony
That professionalisation has underpinned the success of the ninth Women's World Cup, which ended on Sunday with Spain beating England by a single goal in a final that pitted the two European countries with the strongest domestic leagues against each other. Attracting record crowds and television audiences, the tournament buoyed hopes that the women's game can start to bridge the yawning financial gap that exists with the men. TV BLACKOUTIn broadcast rights, the women's game has struggled to compete. The FIFA president, Gianni Infantino, threatened Europe's "Big 5" nations with a TV World Cup blackout unless their broadcasters upped their offers. But both Chadwick and Carlota Planas, a Spain-based women's' football agent representing several World Cup players, argued that the women's game now offers the values of tenacity, resilience and togetherness, which can appeal to advertisers.
Persons: Stoke City's, Molly Holder, Spain's, Olga Carmona, Sunday's, Gianni Infantino, Jill Ellis, Lisa Parfitt, Jill Scott, Chloe Kelly, Ella Toone, Kieran Maguire, Simon Chadwick, Chadwick, Carlota Planas, Planas, let's, Holder, Kate Holton, Nick Mulveney, Helen Reid, Suban Abdulla, Matt Scuffham Organizations: Stoke City women's, Reuters, Stoke City FC, REUTERS Acquire, Stoke, Spain, England, Deloitte, Real Madrid, Real Madrid men's, FIFA, Women, Football, Germany, University of Liverpool, Wembley, Super League, men's Premier League, Manchester City, Arsenal, School, Thomson Locations: Stoke, Trent, Britain, Handout, STOKE, England, MADRID, Spain, France, Germany, Italy, United States, Manchester, Chelsea, Liverpool, Sydney, London
Lionel Messi is already impacting US soccer
  + stars: | 2023-06-14 | by ( Matias Grez | ) edition.cnn.com   time to read: +7 min
CNN —Lionel Messi’s move to Inter Miami is yet to be finalized, but already his impact on Major League Soccer is being felt. “For those people who want to be able to say: ‘I was there at Lionel Messi’s first MLS game,’ demand will exceed supply. Before Messi, Pelé was arguably the most famous face to play soccer in the US. Inter Miami fans have had very little to cheer this season, sitting bottom of the Eastern Conference. CNN has reached out to Major League Soccer, Inter Miami, Messi’s representative, Apple and David Beckham, who is part of Inter Miami’s ownership team, to confirm the financial details.
Persons: Lionel Messi’s, David Beckham, Zlatan Ibrahimovic, Wayne Rooney, Messi, Jim Curtin, , Messi’s, Kieran Maguire, The Price, ” Maguire, He’s, Cruz Azul, , TickPick, StubHub, Pelé, George Tiedemann, Lionel Messi, Beckham, Maguire, , we’ve, Michael Reaves, Eddy, “ He’s, it’s Messi Organizations: CNN, Inter Miami, Major League Soccer, Philadelphia Union, ” Inter Miami, Football, University of Liverpool Management School, CNN Sport, Premier League, Arsenal, MLS, Inter Miami’s Leagues, Cruz, New York Red Bulls, Big Apple, Inter, Los Angeles FC, Eastern Conference, NFL, MLB, NHL, New York Cosmos, North American Soccer League, Argentine, Los Angeles Galaxy, NBA, , Miami, Apple TV’s, Apple, Leagues Cup Locations: Manchester City, Los, Miami, United States, USA, Canada, Mexico, States, Saudi, Saudi Arabia
Daisy Dyke has visited 59 countries around the world, including Greece, New Zealand and Brazil. Growing up, I was obsessed with nature documentaries, and from a young age knew that I wanted to travel and explore. After about eight months of traveling, I went back to England and attended the University of Liverpool. I knew I wanted to travel for a couple of years and would need to work while doing that. People have a misconception that digital nomads don't workAs of 2023, I've visited 59 countries.
Trendy weight-loss drugs cost much more in the US than in other countries. The price of semaglutide, the drug sold as Wegovy, was three times higher in the US than in the UK. If you're searching for affordable weight-loss drugs, you may be better off looking outside of the US. New weight-loss drugs are unaffordableGetty ImagesWegovy and Ozempic are part of a class of weight-loss drugs known as GLP-1 agonists that have soared in popularity in recent months. Drug prices are highest in the USThe variation in prices for weight-loss drugs across the world is striking.
The ocean’s mesopelagic zone, also called the “twilight zone,” is located between 656 feet and 3,280 feet (200 meters to 1,000 meters) below the surface. The twilight zone also a crucial habitat for marine life that dives in search of prey, like sharks, or lanternfish that hide in the twilight zone during the day and swim to the surface waters to feed at night. Small crustaceans known as Megacalanus princeps live in the ocean's twilight zone at a depth of 1,000 meters in the Northeast Atlantic. Natural Visions/Alamy Stock PhotoNew research warns that the climate crisis could reduce life in the twilight zone between 20% and 40% by the end of the century. “What we really need to protect the (twilight zone) is to stop, or at least slow down, the high rate of change that we are subjecting our planet’s climate to.”
Prehistoric humans were surprisingly creative cooks
  + stars: | 2022-11-22 | by ( Katie Hunt | ) edition.cnn.com   time to read: +6 min
CNN —Stone Age cooks were surprisingly sophisticated, combining an array of ingredients and using different techniques to prepare and flavor their meals, analysis of some the earliest charred food remains has suggested. (From left) Breadlike food was found in Franchthi Cave in Greece; pulse-rich food with wild peas was uncovered in Shanidar Cave in northern Iraq. The charred food remains from Franchthi Cave dated from 12,000 years ago, when it was also occupied by hunter-gatherer Homo sapiens. Much research on prehistoric diets has focused on whether early humans were predominantly meat eaters, but Kabukcu said it was clear they weren’t just chomping on woolly mammoth steaks. A Neanderthal hearth was unearthed at Shanidar Cave, where charred plant remains were also found.
Epoch Biodesign, a startup converting plastic to chemicals using enzymes, has raised $14.5 million. Epoch Biodesign uses plastic-eating enzymes as a base and scientifically alters them to produce a specific chemical from the consumed plastic. Epoch Biodesign is also developing enabling technologies to do this cheaper, faster, better, and at greater scale. This is a colony picker, one the machines used test and select Epoch Biodesign's enzymes in the lab. In the long run, Epoch Biodesign expects to license out its technology so it isn't running facilities itself.
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